A previously uncharacterized two-component signaling system in uropathogenic Escherichia coli coordinates protection against host-derived oxidative stress with activation of hemolysin-mediated host cell pyroptosis.

Uropathogenic Escherichia coli (UPEC) deploy an array of virulence factors to successfully establish urinary tract infections.Hemolysin is a pore-forming toxin, and its expression correlates with the severity of UPEC infection.Two-component signaling systems (TCSs) are a major mechanism by which bacteria sense environmental cues and respond by init

read more

Cognitive pediatric tele-assessment: a scoping review

Cognitive tele-assessment (CTA) adoption has increased considerably recently, in parallel with the maturation of the digital technologies that enable it, and the push to move assessment to the online format during the COVID-19 pandemic in 2019.This mode of assessment stems from remote assessment applications that originated in general wahl power gr

read more

Sobbing: Phonotherapeutic Characteristics and Possibilities

Introduction: Sobbing is a reflex action that occurs because of a diaphragmatic spasm at the moment of the inspiration with the simultaneous glottic closure, followed by a characteristic noise.In our clinical practice we have found patients who begin to present with persistent sobbing after a neurologic clinical event.Objective: To characterize sob

read more